SGC-GAK-1: a chemical probe for cyclin G associated kinase (GAK)
C. R. M. Asquith, B.-T. Berger, J. Wan, J. M. Bennett, M. P. East, J. M. Elkins, O. Fedorov, P. H. Godoi, D. M. Hunter, S. Knapp, S. Mueller, C. I. Wells, H. S. Earp, T. M. Willson, W. J. Zuercher
The paper describes SGC-GAK-1, a selective GAK inhibitor, and identifies a related compound that inhibits RIPK2 without GAK activity, providing tools to study GAK and RIPK2 biology.
bioRxiv · Jul 25, 2018Cell Biology