Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities
M. L. Russell, A. Souquette, D. M. Levine, E. K. Allen, G. Kuan, N. Simon, A. Balmaseda, A. Gordon, P. Thomas, F. A. Matsen, P. G. Bradley
The paper infers genetic loci influencing V(D)J recombination probabilities by combining TCR repertoires and genome-wide genotypes from a human cohort.
bioRxiv · Sep 17, 2021Immunology