N. Simon

eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration

The paper identifies eEF2 as a prognostic biomarker for dense connective tissue repair outcomes and shows it regulates cellular processes to improve healing.

Statistical inference reveals the role of length, breathing, and nucleotide identity in V(D)J nucleotide trimming

The paper uses a probabilistic model to analyze TCRβ repertoire data and identifies sequence features that predict nucleotide trimming during V(D)J recombination.

Bayesian Pharmacometrics Analysis of Baclofen for Alcohol Use Disorder

This study uses Bayesian pharmacometrics to estimate Baclofen PK parameters in AUD patients, showing accurate predictions using HMC algorithms with informative priors.

Viral infection impacts the 3D subcellular structure of the abundant marine diatom Guinardia delicatula

This study uses 3D confocal microscopy to observe how viral infection alters the subcellular structure of the diatom Guinardia delicatula.

Insight into diatoms diversity at two European coastal sites (LTER-MC in the Mediterranean Sea and SOMLIT-Astan in the Western English Channel) using a DNA metabarcoding approach

The paper uses DNA metabarcoding to analyze diatom diversity at two coastal sites, finding shared ASVs and suggesting internal growth factors influence diversity patterns.

Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities

The paper infers genetic loci influencing V(D)J recombination probabilities by combining TCR repertoires and genome-wide genotypes from a human cohort.

Seasonal temporal dynamics of marine protists communities in tidally mixed coastal waters

The paper analyzes seasonal changes in marine protist communities using long-term data from microscopy and metabarcoding, revealing seasonal patterns and environmental influences.

An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations

This study shows that interbacterial toxins like DddA can induce mutations in surviving bacterial populations, promoting adaptation through direct DNA mutagenesis.

A thermal trade-off between viral production and degradation drives phytoplankton-virus population dynamics

The paper models how temperature affects viral production and degradation in phytoplankton-virus interactions, showing climate change could alter host-virus dynamics.