Cancer BiologybioRxivPreprint
HOXD13 is a direct EWS-FLI1 target and moderates fusion-dependent transcriptional states
A. A. Apfelbaum, F. Wu, A. Hawkins…·E. R. Lawlor
The paper identifies HOXD13 as a direct target of EWS-FLI1 and shows it modulates transcriptional states in Ewing sarcoma by antagonizing EWS-FLI1-dependent gene repression.