Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma
A. Flesken-Nikitin, C. Q. Ralston, D.-J. Fu, A. J. De Micheli, D. J. Phuong, B. A. Harlan, A. P. Armstrong, D. McKellar, S. Ghuwalewala, J. C. Schimenti, B. D. Cosgrove, A. Y. Nikitin
The paper identifies pre-ciliated tubal epithelial cells as a cancer-prone state in high-grade serous ovarian carcinoma by analyzing mouse uterine tube cell states and lineage dynamics.
bioRxiv · Dec 12, 2023Cancer Biology