Author

D. McKenna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Khoo· 1 shared B. Bassey-Archibong· 1 shared C. Chokshi· 1 shared C. Vandier· 1 shared C. Venugopal· 1 shared D. Bakhshinyan· 1 shared D. O'Reilly· 1 shared D. Piyasena· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Khoo

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2 papers

Recent·Most cited

CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer

D. O'Reilly, T. J. Downing, S. Kouba, M. Potier-Cartereau, D. McKenna, C. Vandier, P. J. Buchanan

This study shows that increased CaV1.3 promotes resistance to androgen deprivation in prostate cancer by enhancing store operated calcium entry.

bioRxiv · Sep 3, 2021Cancer Biology

Hitting more birds with one stone: CD70 as an actionable immunotherapeutic target in recurrent glioblastoma

M. Seyfrid, W. Maich, V. M. Shaikh, N. Tatari, D. Upreti, D. Piyasena, M. Subapanditha, N. Savage, D. McKenna, L. Kuhlmann, A. Khoo, S. K. Salim, B. Bassey-Archibong, W. D. Gwynne, C. Chokshi, , S. K. Singh

This study identifies CD70 as a therapeutic target for recurrent glioblastoma, showing that CD70 knockdown reduces tumorigenicity and CD70 CAR-T therapy improves survival in animal models.

bioRxiv · Jun 2, 2021 · PreprintCancer Biology