Author

A. Khoo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. Chokshi· 2 shared C. Venugopal· 2 shared D. Bakhshinyan· 2 shared J. Moffat· 2 shared K. R. Brown· 2 shared N. Savage· 2 shared N. Tatari· 2 shared P. Vora· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

C. Chokshi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Droplet based low input proteomic platform for rare cell populations

M. Waas, A. Khoo, P. Tharmapalan, C. W. McCloskey, M. Govindarajan, B. Zhang, S. Khan, P. Waterhouse, R. Khokha, T. Kislinger

DROPPS enables high-fidelity proteomic profiling of rare cell populations with low input, revealing CD36 as a marker of progenitor capacity in mammary basal cells.

bioRxiv · Sep 11, 2023 · PreprintBiochemistry

Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma

M. A. Qazi, S. K. Salim, K. R. Brown, N. Mikolajewicz, N. Savage, H. Han, M. K. Subapanditha, D. Bakhshinyan, A. Nixon, P. Vora, K. Desmond, C. Chokshi, M. Singh, A. Khoo, A. Macklin, , S. K. Singh

This study characterizes the minimal residual disease state in glioblastoma, revealing distinct evolutionary trajectories and immunomodulatory signatures associated with recurrence.

bioRxiv · Jan 28, 2022Cancer Biology

Hitting more birds with one stone: CD70 as an actionable immunotherapeutic target in recurrent glioblastoma

M. Seyfrid, W. Maich, V. M. Shaikh, N. Tatari, D. Upreti, D. Piyasena, M. Subapanditha, N. Savage, D. McKenna, L. Kuhlmann, A. Khoo, S. K. Salim, B. Bassey-Archibong, W. D. Gwynne, C. Chokshi, , S. K. Singh

This study identifies CD70 as a therapeutic target for recurrent glioblastoma, showing that CD70 knockdown reduces tumorigenicity and CD70 CAR-T therapy improves survival in animal models.

bioRxiv · Jun 2, 2021 · PreprintCancer Biology