Interferon regulatory factor 3 upregulates the Treg recruitment factor CCL22 in response to double-stranded DNA in cancer cells
J. Kim, J. Pena, H. McQueen, L. Kong, D. Michael, P. Cook
This study identifies IRF3 as a key regulator of CCL22 expression in cancer cells in response to dsDNA, linking STING activation to immunosuppressive mechanisms.
bioRxiv · Mar 8, 2022 · PreprintCancer Biology