Distinct Activation Mechanisms of CXCR4 and ACKR3 Revealed by Single-Molecule Analysis of their Conformational Landscapes
C. T. Schafer, R. F. Pauszek, M. Gustavsson, T. M. Handel, D. P. Millar
This study uses single-molecule FRET to compare conformational dynamics of CXCR4 and ACKR3, revealing distinct activation mechanisms and conformational landscapes.
bioRxiv · Oct 31, 2023Biophysics