Comparative analysis of Formyl peptide receptor 1 and Formyl peptide receptor 2 reveals shared and preserved signaling profiles
U. Rescher, C. A. Raabe, D. Pajonczyk, M. F. Sternschulte, M. Bermudez, O. Soehnlein
The paper compares FPR1 and FPR2 signaling profiles using agonists, finding shared core signatures and low activity ratios for FPR2 agonists, challenging assumptions about receptor-specific inflammatory profiles.
bioRxiv · Feb 8, 2024 · PreprintPharmacology & Toxicology