Author

E. Wardelmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Trautmann· 2 shared W. Hartmann· 2 shared A. Kuntze· 1 shared B. Altvater· 1 shared B. E. Michels· 1 shared C. Hartmann· 1 shared C. Roessig· 1 shared C. Scholl· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

M. Trautmann

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Author profile →

3 papers

Recent·Most cited

Exploiting WEE1 kinase activity as FUS::DDIT3-dependent therapeutic vulnerability in myxoid liposarcoma

L. Heinst, K. S. Lee, R. Berthold, I. Isfort, S. Wosnig, A. Kuntze, S. Hafner, B. Altvater, C. Roessig, P. Aman, E. Wardelmann, C. Scholl, W. Hartmann, S. Froehling, M. Trautmann

This study identifies WEE1 kinase activity as a therapeutic target in FUS::DDIT3-driven myxoid liposarcoma by showing its role in replication stress tolerance and cell survival.

Clinical Cancer Research · Aug 29, 2024Peer-reviewedCancer Biology

A novel adhesive complex at the base of intestinal microvilli

C. Hartmann, E.-M. Thuering, B. E. Michels, D. Pajonczyk, S. Leussink, L. Greune, F. Brinkmann, M. Glaesner-Ebnet, E. Wardelmann, T. Zobel, M. A. Schmidt, V. Gerke, K. T. Ebnet

The paper identifies a novel adhesive complex at the base of intestinal microvilli composed of TMIGD1, EBP50, and ezrin, and describes its regulation by phosphorylation and phosphatase activity.

bioRxiv · Jan 25, 2021 · PreprintCell Biology

Focal adhesion kinase confers pro-migratory and anti apoptotic properties and is a potential therapeutic target in Ewing sarcoma

K. Steinestel, E.-P. Jansen, M. Trautmann, U. Dirksen, J. Rehkamper, J.-H. Mikesch, J. S. Gerke, M. F. Orth, G. Sannino, E. Wardelmann, T. G. P. Grunewald, W. Hartmann

This study shows FAK promotes migration and prevents apoptosis in Ewing sarcoma via Y397 phosphorylation, suggesting FAK inhibitors could target metastasis.

bioRxiv · Apr 12, 2019Cancer Biology