Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
C. Plattner, G. Lamberti, P. Blattmann, A. Kirchmair, D. Rieder, Z. Loncova, G. Sturm, S. Scheidl, M. E. Ijsselsteijn, G. Fotakis, A. Noureen, R. Lisandrelli, N. Boeck, N. Nemati, A. Krogsdam, , Z. Trajanoski
The paper uses patient-derived organoids and phosphoproteomics to study signaling crosstalk in colorectal cancer and identify off-target effects of kinase inhibitors.
bioRxiv · Sep 16, 2022Cancer Biology