Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity
D. Rozanov, A. Cheltsov, A. Nilsen, C. Boniface, J. Korkola, J. Gray, J. Tyner, C. E. Tognon, G. B. Mills, P. Spellman
The paper identifies key factors distinguishing non-toxic and toxic compounds targeting mitochondria in cancer therapy using SAR studies and a mathematical model.
bioRxiv · Oct 1, 2018Cancer Biology