Metformin impairs trophoblast metabolism and differentiation in dose dependent manner
S. K. Nashif, R. M. Mahr, S. Jena, S. Jo, A. B. Nelson, D. Sadowski, P. A. Crawford, P. Puchalska, E. U. Alejandro, M. D. Gearhart, S. A. Wernimont
This study shows that high-dose metformin impairs trophoblast metabolism and differentiation, while therapeutic doses do not.
bioRxiv · Feb 14, 2023 · PreprintCell Biology