S. Jo

Self-assembly of microstructured protein coatings with programmable functionality for fluorescent biosensors

This paper develops a genetically programmable protein coating platform for a smartphone-based fluorescent biosensor to measure calcium concentrations and detect hypercalcemia.

HIGH THROUGHPUT QUANTITATION OF HUMAN NEUTROPHIL RECRUITMENT AND FUNCTIONAL RESPONSES IN AN AIR-BLOOD BARRIER ARRAY

The paper develops a high-throughput assay to study neutrophil recruitment and function in an air-blood barrier array, showing improved throughput and sample efficiency compared to existing methods.

The distinct roles of MSH2 and MLH1 in basal-like breast cancer and immune modulation

This study identifies distinct roles of MSH2 and MLH1 in basal-like breast cancer, showing MSH2 promotes metastasis while MLH1 enhances it, and reveals MSH2's role in immune modulation through IFNAR1 regulation.

Electrocatalytic on-site oxygenation for transplanted cell-based-therapies

This paper introduces an electrocatalytic system for on-site oxygen production to support cell therapies under hypoxic conditions.

Metformin impairs trophoblast metabolism and differentiation in dose dependent manner

This study shows that high-dose metformin impairs trophoblast metabolism and differentiation, while therapeutic doses do not.

Endowing Universal CAR T-cell with Immune-Evasive Properties using TALEN-Gene Editing.

This paper develops a novel CAR T-cell scaffold with immune-evasive properties to enable universal allogeneic CAR T-cell therapy.

Single-cell perturbation dissects transcription factor control of progression speed and trajectory choice in early T-cell development

The paper uses single-cell CRISPR perturbation to study how transcription factors influence progression speed and trajectory choice in early T-cell development.

IgG surface mobility promotes antibody-dependent cellular phagocytosis by Syk and Arp2/3 mediated reorganization of Fcγ receptors in macrophages.

This study shows that IgG surface mobility enhances antibody-dependent cellular phagocytosis (ADCP) through Syk and Arp2/3-mediated reorganization of Fcγ receptors in macrophages.

Molecular mapping of qBK1Z, a major QTL for bakanae disease resistance in rice

This study identifies a major QTL, qBK1Z, for bakanae disease resistance in rice using QTL mapping in recombinant inbred lines derived from a resistant and susceptible variety.