Antidiabetic drug therapy alleviates type 1 diabetes in mice by promoting pancreatic alpha-cell transdifferentiation
D. Sarnobat, C. R. Moffett, N. Tanday, F. Reimann, F. M. Gribble, P. R. Flatt, A. I. Tarasov
This study shows antidiabetic drugs like liraglutide and dapagliflozin alleviate type 1 diabetes in mice by reducing beta-cell apoptosis and promoting alpha-cell transdifferentiation into beta-cells.
bioRxiv · Aug 3, 2020Physiology