Protein design using structure-based residue preferences
D. Ding, A. Y. Shaw, S. Sinai, N. J. Rollins, N. Prywes, D. Savage, M. T. Laub, D. S. Marks
This paper introduces a method to design functional proteins using residue preferences derived from structural data, showing high accuracy in predicting combinatorial mutation effects.
bioRxiv · Oct 31, 2022Bioengineering