Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments
D. Schaff, S. Singh, K.-B. Kim, M. Sutcliffe, K.-S. PARK, K. Janes
This study identifies regulatory state heterogeneity in small-cell lung cancer cells in vitro and in vivo, showing increased fragmentation in the liver and its prognostic relevance in human tumors.
bioRxiv · Mar 30, 2020Cancer Biology