A de novo approach to inferring within-host fitness effects during untreated HIV-1 infection
C. Illingworth, J. Raghwani, D. Serwadda, N. K. Sewankambo, M. Robb, M. Eller, A. Redd, T. Quinn, K. Lythgoe
This study uses a novel multi-locus method to infer selection effects on HIV-1 variants in untreated patients, finding a broad distribution of beneficial fitness effects with many variants under weak selection.
bioRxiv · Nov 6, 2019Evolutionary Biology