Evolutionary BiologybioRxiv
A de novo approach to inferring within-host fitness effects during untreated HIV-1 infection
C. Illingworth, J. Raghwani, D. Serwadda…·K. Lythgoe
This study uses a novel multi-locus method to infer selection effects on HIV-1 variants in untreated patients, finding a broad distribution of beneficial fitness effects with many variants under weak selection.
DOI 10.1371/journal.ppat.1008171