Global hypo-methylation in a subgroup of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape
J. Boot, G. Rosser, D. Kancheva, C. Vinel, Y. M. Lim, N. Pomella, X. Zhang, L. Guglielmi, D. Sheer, M. Barnes, S. Brandner, S. Nelander, K. Movahedi, S. Marino
The paper identifies a glioblastoma subgroup with global hypo-methylation and astrocytic features linked to invasion and immune changes.
bioRxiv · Feb 15, 2022 · PreprintCancer Biology