Author

D. Singleton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:comparative / phylogenetic analysis· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Choi· 2 shared G. Whittaker· 2 shared A. Stout· 1 shared E. Kots· 1 shared H. Weinstein· 1 shared J. Millet· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersMicrobiology

A. Choi

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2 papers

Recent·Most cited

Analysis of the molecular determinants for furin cleavage of the spike protein S1/S2 site in defined strains of the prototype coronavirus murine hepatitis virus (MHV)

A. Choi, E. Kots, D. Singleton, H. Weinstein, G. Whittaker

The paper analyzes the molecular determinants of furin cleavage of MHV spike protein S1/S2 site, identifying structural requirements and sequence variations affecting cleavage efficiency.

bioRxiv · Jan 11, 2023Microbiology

In vitro and computational analysis of the putative furin cleavage site (RRARS) in the divergent spike protein of the rodent coronavirus AcCoV-JC34 (sub-genus luchacovirus)

A. Choi, D. Singleton, A. Stout, J. Millet, G. Whittaker

The paper analyzes the spike protein of AcCoV-JC34, identifying a putative furin cleavage site that is not cleaved by furin, suggesting a potential progenitor sequence for viral emergence.

bioRxiv · Dec 16, 2021 · PreprintMicrobiology