Engineering improved Cas13 effectors for targeted post-transcriptional regulation of gene expression
E. J. Charles, S. E. Kim, G. J. Knott, D. Smock, J. Doudna, D. F. Savage
This paper engineers improved Cas13 effectors for targeted post-transcriptional regulation, showing efficient translational repression in bacteria and exon skipping in human cells.
bioRxiv · May 26, 2021 · PreprintBioengineering