Pharmacological Characterisation of Novel Adenosine Receptor A3R Antagonists
K. Barkan, P. Lagarias, M. Stampelou, D. Stamatis, S. Hoare, K.-N. Klotz, E. Vrontaki, A. Kolocouris, G. Ladds
This study characterizes a selective A3R antagonist, K18, and identifies its binding mode through molecular dynamics simulations and mutagenesis.
bioRxiv · Apr 28, 2020Pharmacology & Toxicology