Dual RNA-seq reveals a type 6 secretion system-dependent blockage of TNF-α signaling and BicA as a Burkholderia pseudomallei virulence factor important during gastrointestinal infection
J. I. Sanchez-Villamil, D. Tapia, N. Khakhum, S. G. Widen, A. G. Torres
This study identifies the type 6 secretion system (T6SS) and the BicA gene as critical for Burkholderia pseudomallei virulence during gastrointestinal infection using dual RNA-seq and mutant analysis.
bioRxiv · Apr 22, 2022Microbiology