Author

D. Temko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

I. Tomlinson· 2 shared A. Sottoriva· 1 shared B. Schuster-Boeckler· 1 shared B. Werner· 1 shared C. P. Barnes· 1 shared D. Nichol· 1 shared G. D. Cresswell· 1 shared I. Spiteri· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

I. Tomlinson

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2 papers

Recent·Most cited

Measuring single cell divisions in human cancers from multi-region sequencing data

B. Werner, J. Case, M. J. Williams, K. Chkhaidze, D. Temko, J. Fernandez-Mateos, G. D. Cresswell, D. Nichol, W. Cross, I. Spiteri, W. Huang, I. Tomlinson, C. P. Barnes, T. A. Graham, A. Sottoriva

This study measures single-cell division rates and survival in human cancers using multi-region sequencing data, revealing per-cell mutation and survival rates across different cancer types and healthy tissues.

bioRxiv · Feb 25, 2019 · PreprintCancer Biology

The effects of mutational process and selection on driver mutations across cancer types

D. Temko, I. Tomlinson, S. Severini, B. Schuster-Boeckler, T. Graham

This study uses public cancer sequencing data to show that mutational processes influence driver mutation presence, but selection often has a larger impact across cancer types.

bioRxiv · Jun 12, 2017Cancer Biology