Spatio-Genetic and Phenotypic Modelling Elucidates Resistance and Re-Sensitisation to Treatment in Heterogeneous Melanoma
A. Hodgkinson, L. Le Cam, D. Trucu, O. Radulescu
This paper models drug resistance and re-sensitisation in melanoma using mathematical frameworks, showing that spatio-genetic heterogeneity and treatment sequencing impact therapeutic outcomes.
bioRxiv · Nov 7, 2018Cancer Biology