Author

D. V. Lessard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

C. L. Berger· 3 shared A. G. Hendricks· 1 shared H. L. H. Malaby· 1 shared J. Stumpff· 1 shared L. Balabanian· 1 shared P. W. Stevens· 1 shared P. W. Wiseman· 1 shared P. Yaninska· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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3 shared papersBiophysics

C. L. Berger

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Tau differentially regulates the transport of early endosomes and lysosomes

L. Balabanian, D. V. Lessard, P. Yaninska, P. W. Stevens, P. W. Wiseman, C. L. Berger, A. G. Hendricks

This study shows that tau differentially regulates the transport of early endosomes and lysosomes by inhibiting kinesin motors, with lysosomes being more affected than early endosomes.

bioRxiv · Nov 1, 2021Biophysics

The Microtubule Associated Protein Tau Regulates KIF1A Pausing Behavior and Motility

C. L. Berger, D. V. Lessard

This paper identifies Tau-mediated regulation of KIF1A pausing behavior and motility through competitive interaction with tubulin C-terminal tails, linking it to neurodegenerative disease mechanisms.

bioRxiv · Aug 11, 2021 · PreprintBiophysics

The Human Kinesin Kif18A’s Neck Linker Permits Navigation of Microtubule Bound Obstacles within the Mitotic Spindle

H. L. H. Malaby, D. V. Lessard, C. L. Berger, J. Stumpff

This study shows that the long neck linker of Kif18A enables it to navigate microtubule-associated protein obstacles to accumulate at K-fiber plus-ends during mitosis.

bioRxiv · Jul 7, 2018Cell Biology