Induction of expansion of ex vivo NK cells using a new feeder cell built in Brazil. An extended flow cytometry evaluation of K562.mbIL21.4BBL
C. M. Watanabe, C. Ishihama Suzuki, A. Marins dos Santos, T. P. A. Aloia, G. Lee, D. Wald, O. K. Okamoto, J. T. C. d. Azevedo, J. A. P. d. Godoy, F. P. S. Santos, R. Weinlich, L. N. Kerbauy, J. M. Kutner, R. d. M. A. Paiva, N. Hamerschlak
This paper develops a Brazilian feeder cell, K562.Clone1, which expands NK cells ex vivo more than 100-fold while preserving their antitumor activity.
bioRxiv · Feb 23, 2024 · PreprintCancer Biology