Unravelling cytosolic delivery of endosomal escape peptides with a quantitative endosomal escape assay (SLEEQ)
S. L. Y. Teo, J. J. Rennick, D. Yuen, H. Al-Wassiti, A. P. R. Johnston, C. W. Pouton
This study develops a sensitive assay to evaluate endosomal escape of peptides and finds that positive charge enhances delivery through membrane association, not escape efficiency.
bioRxiv · Aug 20, 2020Cell Biology