Author

C. W. Pouton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. P. R. Johnston· 2 shared J. J. Rennick· 2 shared S. L. Y. Teo· 2 shared A. Takanashi· 1 shared C. J. Nowell· 1 shared C. W. Tan· 1 shared C. Y. Wong· 1 shared D. F. J. Purcell· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

A. P. R. Johnston

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3 papers

Recent·Most cited

ImmunologybioRxivOct 4, 2023

mRNA vaccines encoding membrane-anchored receptor-binding domains of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting

H. A. Al-Wassiti, S. A. Fabb, S. L. Grimley…·C. W. Pouton

DOI 10.1016/j.omtm.2024.101380

mouseexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivApr 13, 2022

Resolving subcellular pH with a quantitative fluorescent lifetime biosensor

J. J. Rennick, C. J. Nowell, C. W. Pouton, A. P. R. Johnston

This paper introduces pHLIM, a method to quantify sub-cellular pH using fluorescent lifetime imaging and deep learning, demonstrating its application in measuring pH changes in cellular compartments.

DOI 10.1038/s41467-022-33348-z

fluorescence / live-cell microscopydeep learning

𝕏 PostBluesky

Cell BiologybioRxivAug 20, 2020

Unravelling cytosolic delivery of endosomal escape peptides with a quantitative endosomal escape assay (SLEEQ)

S. L. Y. Teo, J. J. Rennick, D. Yuen…·C. W. Pouton

This study develops a sensitive assay to evaluate endosomal escape of peptides and finds that positive charge enhances delivery through membrane association, not escape efficiency.

DOI 10.1038/s41467-021-23997-x

experimental assaydrug response / drug discovery

𝕏 PostBluesky