Author

Dan Hao

University of Kentucky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Physiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ling GuoiD· 3 shared Misa ItoiD· 3 shared Qian WangiD· 3 shared Xiang‐An LiiD· 3 shared Bin HuangiD· 2 shared Chieko MineoiD· 2 shared Jianyao XueiD· 2 shared Philip W. ShauliD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

Ling GuoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of scavenger receptor BI as a scavenger of free heme that is essential for protection against hemolysis

Misa Ito, Jianyao Xue, Ling Guo, Dan Hao, Qian Wang, Alexander H. Williams, Chang‐Guo Zhan, Ailing Ji, Preetha Shridas, Wen Su, Shu Liu, Zhenheng Guo, M GONG, Scott M. Gordon, Bin Huang, , Xiang‐An Li

This study identifies scavenger receptor BI as a critical heme scavenger that protects against hemolysis, showing its therapeutic potential in hemolytic disorders.

Nature Communications · Jul 27, 2026Peer-reviewedPhysiology

Elevated plasma cholesterol causally improves sepsis outcome by promoting hepatic metabolic reprogramming

Qian Wang, Jianyao Xue, Ling Guo, Dan Hao, Misa Ito, Rianna Reese, Bin Huang, Congqing Wu, Xiang‐An Li

This study shows elevated plasma cholesterol improves sepsis survival by promoting hepatic metabolic reprogramming, as demonstrated in both human patients and mouse models.

Frontiers in Immunology · May 11, 2026Peer-reviewedPhysiology

Deficiency in reverse cholesterol transport in mice augments sepsis

Qian Wang, Ling Guo, Dan Hao, Misa Ito, Kaijiang Yu, Ruitao Wang, Chieko Mineo, Philip W. Shaul, Xiang‐An Li

This study shows that liver-specific SR-BI deficiency in mice increases susceptibility to CLP-induced sepsis, highlighting RCT's role in sepsis resistance.

bioRxiv · Apr 26, 2020 · PreprintMolecular Biology