Immune Evasion, Cell-Cell Fusion, and Spike Stability of the SARS-CoV-2 XEC Variant: Role of Glycosylation Mutations at the N-terminal Domain
Pei Li, Julia N. Faraone, Cheng Chih Hsu, Michelle Chamblee, Yajie Liu, Yi-Min Zheng, Yan Xu, Claire Carlin, Jeffrey Craig Horowitz, Rama K. Mallampalli, Linda J. Saif, Eugene M. Oltz, Daniel Jones, Jiànróng Lǐ, Richard J. Gumina, , Shan‐Lu Liu
This study examines how glycosylation mutations in the NTD of the SARS-CoV-2 XEC variant affect neutralizing antibody responses, cell-cell fusion, and spike stability.
Journal of Virology · Mar 26, 2025Peer-reviewedMolecular Biology