Evolutionary BiologybioRxiv
Comparison of the theoretical and real-world evolutionary potential of a genetic circuit.
Manuel Razo-Mejia, James Boedicker, Daniel Jones…·Rob Phillips
The paper develops a model to study how promoter sequence variations affect gene expression and evolutionary potential in the lac operon using thermodynamic and binding energy data.
DOI 10.1088/1478-3975/11/2/026005