Retinal degeneration in a mouse model of CRB1 disease rescued by the photoreceptor-specific CRB1-B isoform
Ekta Dembla, Juan C. Valdez‐Lopez, Christopher Kozlowski, Charlotte Reedy, Lin Yu, Mayur Dembla, Daniel Sul, Ariane Pendragon, Ying Hao, Jeremy N. Kay
This study shows that restoring the CRB1-B isoform in photoreceptors rescues retinal degeneration in a mouse model of CRB1 disease by preserving adherens junctions.
bioRxiv · Aug 26, 2026 · PreprintNeuroscience