Differential contribution of HCN1 and HCN4 to the synchronisation of sinoatrial pacemaker cells
Konstantin Hennis, Chiara Piantoni, Martina Orabona, Linh Tran Pham, Michael Schänzler, Natalie Auerbach, Michael Hoerzing, Yakun Wu, René Rötzer, Andra Kohlrautz, Colin Feldmann, Mariano Gonzalez Pisfil, Daniela Krück, Julia Rilling, Beate Averbeck, , Christian Wahl‐Schott
This study investigates the roles of HCN1 and HCN4 in synchronizing sinoatrial pacemaker cells, finding HCN1 is essential for fast synchronisation while HCN4 is not.
bioRxiv · Dec 18, 2025 · PreprintPhysiology