Author

Danielle Hedeen

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:zebrafish· 1

Frequent Co-Authors

Gloria M. SlattumiD· 1 shared Jan HuiskeniD· 1 shared Jody RosenblattiD· 1 shared John FaduliD· 1 shared Mauricio Franco Jin· 1 shared Michael J. Redd· 1 shared Nadja M. Redd· 1 shared Stephan DaetwyleriD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Gloria M. SlattumORCID

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1 paper

Recent·Most cited

Basal extrusion drives cell invasion and mechanical stripping of E-cadherin

John Fadul, Gloria M. Slattum, Nadja M. Redd, Mauricio Franco Jin, Michael J. Redd, Stephan Daetwyler, Danielle Hedeen, Jan Huisken, Jody Rosenblatt

This study shows that basal extrusion drives tumor cell invasion and mechanical shedding of E-cadherin in zebrafish epidermis, with KRas mutations increasing invasion rates and p53 mutations enabling survival at distant sites.

bioRxiv · Nov 6, 2018 · PreprintCancer Biology