Author

John Fadul

The Francis Crick InstituteORCID 0000-0002-8944-0664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1 Organism:zebrafish· 1

Frequent Co-Authors

Jody RosenblattiD· 2 shared Danielle Hedeen· 1 shared Dustin BagleyiD· 1 shared Gloria M. SlattumiD· 1 shared Jan HuiskeniD· 1 shared Konstantinos KalyviotisiD· 1 shared Lily Gates· 1 shared Maria VoronkoviD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Jody RosenblattORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 24, 2026

Starvation improves epithelial fitness by selectively extruding DNA damaged cells

Lily Gates, Dustin Bagley, Konstantinos Kalyviotis…·Jody Rosenblatt

The paper shows that starvation-induced cell extrusion selectively removes DNA-damaged cells, improving tissue fitness through a p53-dependent pathway.

DOI 10.64898/2026.09.01.748489

experimental assay

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Cancer BiologybioRxivPreprintNov 6, 2018

Basal extrusion drives cell invasion and mechanical stripping of E-cadherin

John Fadul, Gloria M. Slattum, Nadja M. Redd…·Jody Rosenblatt

This study shows that basal extrusion drives tumor cell invasion and mechanical shedding of E-cadherin in zebrafish epidermis, with KRas mutations increasing invasion rates and p53 mutations enabling survival at distant sites.

DOI 10.1101/463646

zebrafishimaging

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