DNA and RNA from the same single nucleus reveals interactions between genomic and transcriptomic landscapes in human tumor samples
Siran Li, Joan Alexander, Jude Kendall, Peter Andrews, Elizabeth Rose, Hope Orjuela, Sarah Park, Craig Podszus, Liam Shanley, Nissim Ranade, Patrick Morris, Danielle Stauder, Daniel Bradford, Michael Ronemus, Arvind Rishi, , Dan Levy
This study introduces hybrid BAG-seq to analyze DNA and RNA from single nuclei in tumor samples, revealing genome-transcriptome interactions and tumor heterogeneity.
bioRxiv · Oct 4, 2023 · PreprintGenomics