Mapping the Fragment-Binding Landscape of SARS-CoV-2 nsp14 for Antiviral Drug Discovery
Xinyue Shi, Qian Wang, Danni Dong, Manming Xu, Fatma Al Busaidi, Matthew W. Bowler, Shozeb M Haider, Frank Kozielski
The paper maps the fragment-binding landscape of SARS-CoV-2 nsp14, identifies promising sites for antiviral drug development, and provides a prioritized resource for future inhibitors.
bioRxiv · Oct 22, 2026 · PreprintBiochemistry