Author

Manming Xu

UCL School of Pharmacy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Shozeb M HaideriD· 2 shared Danni Dong· 1 shared Fatma Al Busaidi· 1 shared Frank KozielskiiD· 1 shared Jiwen JiangiD· 1 shared Lin GaoiD· 1 shared Matthew W. BowleriD· 1 shared Qian Wang· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Shozeb M HaiderORCID

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Author profile →

2 papers

Recent·Most cited

Mapping the Fragment-Binding Landscape of SARS-CoV-2 nsp14 for Antiviral Drug Discovery

Xinyue Shi, Qian Wang, Danni Dong, Manming Xu, Fatma Al Busaidi, Matthew W. Bowler, Shozeb M Haider, Frank Kozielski

The paper maps the fragment-binding landscape of SARS-CoV-2 nsp14, identifies promising sites for antiviral drug development, and provides a prioritized resource for future inhibitors.

bioRxiv · Oct 22, 2026 · PreprintBiochemistry

Mechanistic Insights into the Substrate Egress Pathways of Human Glucose Transporters GLUT1 and GLUT9

Manming Xu, Jiwen Jiang, Lin Gao, Saleh Alyemni, Shozeb M Haider

This study uses machine learning and molecular dynamics to analyze substrate egress pathways in GLUT1 and GLUT9, revealing key residues and conformational changes, and showing apigenin inhibits GLUT9 via steric hindrance.

bioRxiv · Mar 4, 2025 · PreprintBiophysics