Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a Legionella pneumophila protein that impinges on a stress response pathway
Dar Hershkovitz, Emy J. Chen, Alexander W. Ensminger, Aisling S. Dugan, K. T. Conway, Alex C. Joyce, Gil Segal, Ralph R. Isberg
The paper identifies LegA7 as a cysteine protease in L. pneumophila that regulates MAPK pathway activation through conserved residues and ankyrin repeats.
mSphere · Aug 22, 2024Peer-reviewedMicrobiology