Author

Alex C. Joyce

Tufts University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Organism:mouse· 1

Frequent Co-Authors

Ralph R. IsbergiD· 2 shared Aisling S. DuganiD· 1 shared Alexander PalmeriD· 1 shared Alexander W. EnsmingeriD· 1 shared Amelia K. Schmidt· 1 shared Andrew Maciver· 1 shared Annika Dankwardt· 1 shared Blake WiedenheftiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

Ralph R. IsbergORCID

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3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedSep 21, 2026

The transcriptional response of Yersinia pseudotuberculosis to macrophage-released metabolites during growth within synthetic microcolonies

Stacie A. Clark, Alexander Palmer, Wenwen Huo…·Ralph R. Isberg

This study investigates how Yersinia pseudotuberculosis responds to macrophage-released metabolites during growth in synthetic microcolonies, identifying nitrosative stress and itaconate as key factors.

DOI 10.1128/mbio.00691-26

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintMay 6, 2025

A prophage-encoded sRNA limits lytic phage infection of adherent-invasive E. coli

Robert S. Brzozowski, Amelia K. Schmidt, Nicole L. Pershing…·Patrick R. Secor

The paper identifies a prophage-encoded sRNA, svsR, that reduces lytic phage infection in AIEC by repressing maltodextrin transport genes, thereby limiting phage receptor expression.

1 citation

E. coliexperimental assay

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MicrobiologymSpherePeer-reviewedAug 22, 2024

Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a Legionella pneumophila protein that impinges on a stress response pathway

Dar Hershkovitz, Emy J. Chen, Alexander W. Ensminger…·Ralph R. Isberg

The paper identifies LegA7 as a cysteine protease in L. pneumophila that regulates MAPK pathway activation through conserved residues and ankyrin repeats.

1 citation

bacteria (other)experimental assay

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