David Bell

Selective targeting of IL-1RAP-dependent eosinophilic inflammation in allergic fungal airway disease

This study identifies IL-1RAP as a target for reducing eosinophilia in allergic fungal airway disease using a mouse model of chronic A. fumigatus exposure.

Discovering plasticity rules that organize and maintain neural circuits

The paper develops a meta-learning approach to discover plasticity rules that organize and maintain sequence-generating neural dynamics in the presence of noise and perturbations.

Unsupervised Restoration of a Complex Learned Behavior After Large-Scale Neuronal Perturbation

The paper shows that songbirds can recover from large-scale neuronal perturbation through unsupervised homeostatic mechanisms, with songs reverting to normal through saltatory recovery.

Precision motor timing via scalar input fluctuations

The paper introduces a model inspired by songbird brains that uses low-dimensional input fluctuations to correct timing errors in motor sequences, verified in zebra finch songs.

Cell-free prototyping strategies for enhancing the sustainable production of polyhydroxyalkanoates bioplastics

This study develops cell-free systems to prototype and optimize polyhydroxyalkanoates biosynthesis, showing whey permeate enhances production and identifies enzymes for metabolite recycling.

A cell-free synthetic biochemistry platform for raspberry ketone production

This paper describes a cell-free synthetic biochemistry platform that achieves high yield raspberry ketone production through an optimised enzymatic pathway.