Author

A. Reed

Guy's and St Thomas' NHS Foundation Trust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Lockhart· 2 shared D. Mucida· 2 shared A. Bilate· 1 shared Alison E. JohniD· 1 shared Anand ShahiD· 1 shared B. F. Cravatt· 1 shared B. S. Reis· 1 shared Bin LiuiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

A. Lockhart

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Selective targeting of IL-1RAP-dependent eosinophilic inflammation in allergic fungal airway disease

Thomas J Williams, James S. Griffiths, Luis Edgardo Gonzales-Huerta, David Bell, A. Reed, Anand Shah, Julian R. Naglik, Darius P. H. Armstrong-James

This study identifies IL-1RAP as a target for reducing eosinophilia in allergic fungal airway disease using a mouse model of chronic A. fumigatus exposure.

Allergy · Feb 11, 2026Peer-reviewedImmunology

Targeting AKAP13 RhoGEF activity ameliorates pro-fibrotic phenotypes driven by the IPF associated AKAP13 risk variant

Bin Liu, James Michael May, Greg Contento, Sara Gangi, Louise A. Organ, Elizabeth Pyman, Iyobel Kibreab, Lan Zhao, Huayang Yao, Rachel Clare Chambers, Iain D. Stewart, A. Reed, Gisli R. Jenkins, Alison E. John

This study shows that an AKAP13 genetic variant promotes fibrosis by altering epithelial signaling, and inhibiting AKAP13's RhoGEF activity reduces fibrotic markers in IPF models.

bioRxiv · Jan 23, 2026 · PreprintGenetics

Dietary protein shapes the profile and repertoire of intestinal CD4+ T cells

A. Lockhart, A. Reed, T. B. R. de Castro, C. Herman, M. C. C. Canesso, D. Mucida

This study shows dietary proteins influence intestinal CD4+ T cell profiles and receptor repertoires, affecting their transcriptional programs and responses to food antigens.

bioRxiv · Apr 11, 2023 · PreprintImmunology

TMEM164 is an acyltransferase that forms ferroptotic polyunsaturated ether phospholipids

A. Reed, T. Ware, H. Li, J. F. Bazan, B. F. Cravatt

The paper identifies TMEM164 as an acyltransferase that produces PUFA ether phospholipids, essential for ferroptosis, and shows its absence reduces these lipids and protects cells from ferroptosis.

bioRxiv · Jul 6, 2022 · PreprintBiochemistry

Vγ usage distinguishes pro- and anti-tumor intestinal γδ T cell subsets

B. S. Reis, P. W. Darcy, I. Z. Khan, O. Eleso, C. Zhu, M. Schernthanner, A. Lockhart, A. Reed, J. Bortolatto, T. Castro, A. Bilate, S. Grivennikov, D. Mucida

The paper identifies Vγ1+ and Vγ7+ γδ T cells as anti-tumor and RORγt+ subsets, including Vγ4+ and Vγ6+, as pro-tumor in colorectal cancer.

bioRxiv · Nov 13, 2021 · PreprintImmunology