Author

DB Longley

Queen's University Belfast

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

C. Higgins· 1 shared Caitriona HolohaniD· 1 shared Emma EvergreniD· 1 shared Greti E. Fiedler· 1 shared H Khawaja· 1 shared J E Fox· 1 shared J FerrisiD· 1 shared J.A. Roberts· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

C. Higgins

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1 paper

Recent·Most cited

Regulation of FLIP(L) and TRAIL-R2 signalling by the SCFSkp2 Ubiquitin Ligase Complex

J.A. Roberts, Caitriona Holohan, Tamas Sessler, J E Fox, C. Higgins, Greti E. Fiedler, Joanna Majkut, Nyree Crawford, JS Riley, H Khawaja, Luke M. Humphreys, J Ferris, Emma Evergren, Paul N. Moynagh, SS McDade, DB Longley

The paper shows SCFSkp2 ubiquitin ligase complex regulates FLIP(L) stability through direct interaction with Cullin-1, affecting TRAIL-R2 signaling and caspase-8 processing.

bioRxiv · Aug 2, 2019 · PreprintMolecular Biology