Plcg2M28L interacts with high fat-high sugar diet to accelerate Alzheimers disease-relevant phenotypes in mice
Adrian L. Oblak, Kevin P. Kotredes, Ravi S. Pandey, Alaina M. Reagan, Cynthia M. Ingraham, Bridget M Perkins, Christopher Lloyd, Deborah Baker, Peter Bor‐Chian Lin, Disha M. Soni, Andy Po‐Yi Tsai, Scott A. Persohn, Amanda A. Bedwell, Kierra Eldridge, Rachael Speedy, , Gareth R. Howell
This study shows that a high fat-high sugar diet interacts with the Plcg2M28L genetic variant to accelerate Alzheimer's disease-like phenotypes in mice.
Frontiers in Aging Neuroscience · Jun 24, 2022Peer-reviewedNeuroscience