Author

Deborah Drage

Babraham Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Wolf ReikiD· 3 shared Fátima SantosiD· 2 shared Mélanie A. Eckersley-MasliniD· 2 shared Oana Kubinyecz· 2 shared Asif NakhudaiD· 1 shared Benjamin Matthew SkinneriD· 1 shared Celia Alda-CatalinasiD· 1 shared Christel KruegeriD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersDevelopmental Biology

Wolf ReikORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Maternal SMARCA5 is required for major ZGA in mouse embryos

Oana Kubinyecz, Deborah Drage, Fátima Santos, Christel Krueger, Hanneke Okkenhaug, Celia Alda-Catalinas, Mélanie A. Eckersley-Maslin, Jasmin Taubenschmid, Wolf Reik

This study shows that maternal SMARCA5 is essential for major ZGA in mouse embryos by regulating promoter and distal regulatory region accessibility and nucleosome positioning.

bioRxiv · Dec 5, 2023 · PreprintDevelopmental Biology

Decoding gene regulation in the mouse embryo using single-cell multi-omics

Ricard Argelaguet, Tim Lohoff, Jingyu Li, Asif Nakhuda, Deborah Drage, Felix Krueger, Lars Velten, Stephen J. Clark, Wolf Reik

A mouse embryo multiome atlas (E7.5 to E8.75) and an unsupervised transcription factor binding predictor; a Brachyury knockout supports its network predictions in neuromesodermal progenitors.

bioRxiv · Jun 15, 2022 · PreprintDevelopmental Biology✦ In-depth digest

Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival

Oana Kubinyecz, Fátima Santos, Deborah Drage, Wolf Reik, Mélanie A. Eckersley-Maslin

This study shows Dppa2/4 are not required for zygotic genome activation but are important for offspring survival, as maternal depletion leads to reduced litter size and increased preweaning lethality.

Development · Dec 15, 2021Peer-reviewedDevelopmental Biology

Differential sperm motility mediates the sex ratio drive shaping mouse sex chromosome evolution

Claudia Cattoni Rathje, Emma Elizabeth Philippa Johnson, Deborah Drage, Christina Patinioti, Giuseppe Silvestri, Nabeel Ahmed Affara, Côme Ialy‐Radio, Julie Cocquet, Benjamin Matthew Skinner, Peter J. I. Ellis

The paper shows that X-bearing sperm have greater motility than Y-bearing sperm in mice with Yq deletions, leading to a skewed sex ratio.

Current Biology · Oct 17, 2019Peer-reviewedDevelopmental Biology