Author

Deng Tan

Hong Kong University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Fan Jiang· 1 shared Huiyu He· 1 shared Jiao MaiD· 1 shared Rui Chen· 1 shared Shu Ping Gu· 1 shared Wei HuangiD· 1 shared Wei Qing XuiD· 1 shared Weimin Fan· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Fan Jiang

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1 paper

Recent·Most cited

Quantitative Control of Noise in Mammalian Gene Expression by Dynamic Histone Regulations

Deng Tan, Rui Chen, Yuejian Mo, Shu Ping Gu, Jiao Ma, Wei Qing Xu, Xibin Lu, Huiyu He, Fan Jiang, Weimin Fan, Yili Wang, Xi Xian Chen, Wei Huang

This study investigates how dynamic histone regulations control noise in gene expression by showing that a positive feedback loop between transcriptional activators and histone acetyltransferases generates epigenetic bistability, leading to large noise, which can be reduced by modulating activator binding.

eLife · Aug 11, 2021Peer-reviewedMolecular Biology