Targeting Tmem63b and Piezo2 in C-fiber low threshold mechanoreceptor: limitation of Vglut3-IRES-Cre
Daniel J. Orlin, Antonio Muñoz, Sage Berryman, Destinee Semidey, Swetha E. Murthy
The paper evaluates the Vglut3-IRES-Cre mouse line for identifying non-PIEZO2 mechanosensors in C-LTMRs, finding it labels these neurons but fails to efficiently delete genes like Tmem63b.
Biophysical Journal · Nov 1, 2025Peer-reviewedNeuroscience